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Leptin: The Satiety Hormone

Leptin, also called satiety hormone, is made by adipose (fat) cells that helps to regulate energy balance by controlling hunger. Leptin is opposed to the actions of ghrelin, called hunger hormone. Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy balance. The regulation of fat stores is deemed to be the primary function of leptin but it also plays in other physiological processes. Besides adipose cells, it is also produced by placenta, ovaries, skeletal muscles, stomach, mammary epithelial cells, and bone marrow.

It circulates in blood in free form and bound to proteins. Leptin levels in blood are higher between midnight and early morning, perhaps suppressing appetite during the night. The diurnal rhythm of blood leptin levels may be modified by meal-timing.

Functions of leptin –

The following are important functions of leptin:

• Primarily, leptin regulates food intake and body weight. It acts on the specific receptors in the hypothalamus to inhibit appetite. When fat mass decreases, the level of plasma leptin falls so that appetite is stimulated until the fat mass is recovered. There is also a decrease in body temperature and energy expenditure is suppressed. Conversely, when fat mass increases, so do leptin levels, thereby suppressing appetite until weight loss occurs. Thus leptin regulates energy intake and fat stores so that weight is maintained within a relatively narrow range.

• Leptin also seems to play an important role in modulating the onset of puberty. For example, undernourished and thin girls take longer to reach puberty than normal girls. Thin girls often fail to ovulate or release an egg from an ovary during menstruation cycles. Reproductive growth and fat stores are, therefore, vital in the regulation of reproduction.

Leptin resistance –

Besides many factors involved in the causation of obesity, an important factors is leptin resistance. Many believe that leptin resistance is the leading driver of fat gain in humans.

The main function of leptin is sending a signal to the brain, “telling” it how much fat is stored in the body’s fat cells. Since leptin is primarily produced by fat cells, obese people have very high levels of leptin. Given the way leptin is supposed to work, these people shouldn’t be eating because their brain should know that they have plenty of energy stored. But the problem is that the leptin signal is not working. As a result, there’s a whole lot of leptin floating around that the brain doesn’t “see” that it is there. This condition is known as leptin resistance. It is now believed to be the main biological abnormality in human obesity.

Therefore, leptin resistance makes the brain change our behavior in order to regain fat that the brain thinks is missing. The brain thinks that we must eat so that we don’t starve to death. Simultaneously, the brain also thinks we need to conserve energy, so it makes us feel lazier and thus makes us burn fewer calories at rest.

Losing weight reduces fat mass, which leads to a significant reduction in leptin levels. When leptin goes down, this leads to hunger, increased appetite, reduced motivation to exercise and decreased amount of calories burned at rest. Basically, the reduced leptin makes the brain think it is starving and so it initiates all sorts of powerful mechanisms to regain that lost body fat.

In other words, the brain actively defends the higher amount of fat mass by compelling us to eat back the lost weight. That is the main reason why yo-yo diets fail to yield the results as the dieters lose a significant amount of fat, only to gain it back.

How to regulate leptin hormone? –

Though leptin resistance is a complex problem, it is not an irreversible one. The following factors will help improve leptin response:

• Reduce sugar and fructose consumption – Minimize using simple starches, refined foods, sugar and fructose. Fructose is a major contributor to insulin and leptin resistance. Fructose disrupts the signals of insulin and leptin, generally by over-taxing the liver because fructose is primarily shuttled to the liver for processing, whereas glucose is primarily shuttled to muscle and fat cells. By reducing the consumption of white sugar and high-fructose corn syrup, we allow liver to do other things like burning fat

• Don’t skip breakfast- Your breakfast should include largely protein and healthy fats. This promotes satiety and gives the body the building blocks to build the hormone.

• Optimize sleep – Try to be in bed by ten o’clock in the night. Take steps to optimize your sleep.

• Avoid frequent eating- When you are constantly eating, even small amounts during the day, it keeps your liver working and doesn’t give hormones a break. Try to space meals at least 3-4 hours apart and don’t eat for at least 3-4 hours before bed. This includes drinks with calories but herbal teas, water, coffee or tea without cream or sugar is fine.

• Exercise regularly- Your workout should include both aerobic exercise and strength training.

• Take more Omegs-3s – Take more Omega-3s by consuming fish, grass fed meats, chia seeds and minimize your Omega-6 consumption by consuming less of vegetable oils, conventional meats, grains, etc. to get lower inflammation and help support healthy leptin levels.

The bottom line –

It is evidently clear that leptin – the satiety hormone – plays an equally important role in regulating hunger as is done by ghrelin. Recently, lot of importance has been attached to leptin resistance in humans, which is now considered to be the driving factor in causing overweight and obesity. There are many factors responsible for causing leptin resistance in humans. The majority of these factors are related to our lifestyle. Initiating positive changes in our lifestyle will help regulate the release of leptin hormone, thereby striking a balance between food intake and body weight.

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The Extremism of Bodybuilders and What it Has to Do With Building Muscle and Getting Rid of Fat

Have you ever wondered why bodybuilders are also extremists? Can we simply say that their extremism helps them with their body building? Or maybe it's that bodybuilding inevitably compels them to become extremists? Whichever is true, we can not deny the fact that the bodybuilders go for the extreme.

During the period in which they are gaining weight or bulking up, bodybuilders take in higher amounts of calories than the usual for them to become bigger. These people usually do this in an out of control or do as they please manner. They do not care either the food they eat is healthy or not as long as they take in large amounts of food. This is certainly a face of the bodybuilder being an extremist.

What the body does is that it immediately stores all the extra calories as fat and considers these fat deposits as 'gold reserves.' The body then utilizes all the needed nutrients and calories for its different processes such as cell repair and maintenance. After which, it opts to store as fats all the excess calories and nutrients.

Bodybuilders who are still in their beginning phase aim to practice two things at the same time: get rid of fat, and build muscle. It is important to remember though that lifting weights will not actually result in loss of weight even if it causes muscle gain. Bodybuilding starters who need to lower their weight will have to reduce their calorie intake and do aerobic exercises that do not cause muscle buildup.

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5 Tips to Build Muscle As Fast As Possible

Learning how to build muscle fast is easy, putting it into practice is the hard part. Most people think that if you lift more, you will gain more muscle mass. This simply isn’t the case.

Building muscle has just as much to do with diet as it does with training, if not more.

You can’t build muscle without a calorie surplus, just as you can’t build muscle without resistance training.

To build muscle fast, you have to optimize your diet as well as training regimen. Here is how to do it.

1. Avoid Low Carb Diets

While low carb diets are great for cutting fat, they won’t help you with gaining muscle mass. You need carbs for fuel so you can exercise more efficiently.

Carbohydrates are important before training sessions, and immediately after training sessions. Carbs are your muscles primary fuel.

By consuming complex carbs you restore glycogen stores within your muscles[1] for further activity and fullness. This is a major factor in how effective a training session is.

2. Avoid All Alcohol

Alcohol, even in small amounts, can have major effects on sleep, and recovery. In a study conducted in 1980, alcohol in small doses (0.8 g/kg) before bedtime, suppressed plasma growth hormone by 70%-75%[2].

If you add in the effects of dehydration and release of cortisol, it’s nothing but a recipe for disaster.

3. Get More Protein

There is a lot of confusion surrounding protein these days. One article says your not eating enough, the other says your eating way too much.

So what is the key?

For moderately active, and highly active adults, it is reasonable to consume around 2-3 grams of protein for every kilogram of bodyweight.[3]

Studies show that too much protein intake has an extremely low chance of negative side effects. Plus, protein is essential in so many bodily functions.

4. Lift Heavy Weights

Protein alone cannot build muscle. To really add-on size, you must lift heavy weights. Or use your bodyweight to achieve the desired resistance.

In the gym, you could focus on lifting 6 sets of 6 reps with a heavy enough weight to reach failure in the last couple of sets. This should be enough to make some serious gains.

5. Switch-up Your Workouts

This doesn’t necessarily mean changing the exercises. Vary your sets and reps, rest time, and intensity. This will help you break through those dreaded plateaus.

I hope this list helps you in achieving your desired physique. But this can only help you if you continually take daily action. Avoid analysis paralysis, and just get to work.

References:

1. Louise M Burke, Bente Kiens & John L Ivy

Carbohydrates and fat for training and recovery

Pages 15-30 | Accepted 07 Aug 2003, Published online: 18 Feb 2007. http://dx.doi.org/10.1080/0264041031000140527

2. Prinz, P.N. et al., The effect of alcohol on sleep and nighttime plasma growth hormone and cortisol concentrations, J. Clin. Endocrinal. Metabol., 50(4), 759-764, 1980

3. Paul Hovan Jr., May 10, 2016

https://www.issaonline.edu/blog/index.cfm/2016/how-much-is-too-much-protein-myths-busted

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Pull-Ups, Chin-Ups, and the Raw Power They Build

Pull-ups (and chin-ups) are an exercise that every serious strength athlete needs to master. They build brute, raw, unadulterated STRENGTH in the upper body -the kind that you cannot get from lifting weights, and certainly not from working out on machines in the gym.

This exercise is more than worth it’s weight in gold, but is unfortunately ignored these days by most people. Let’s face it, when was the last time you saw someone working his butt off on a tough set of pull-ups? Personally, the only thing I’ve seen people do on the monkey bars in the local parks around where I live (and by the way, those monkey bars are great for doing pull-ups) is hang their jackets on them, or loiter by them while yammering on about the latest exercise fad. And that pretty much explains why most people have weak backs, and suffer from a plethora of back related problems.

This ONE exercise will build the back muscles to their fullest. The back is the true foundation of super strength in the upper body (as opposed to the chest, which most people are obsessed about), and this one exercise will work it to the max.It will also build a powerful grip, and strengthen the forearms beyond belief. And the benefits do not stop there – the biceps, triceps, chest, and core are all heavily taxed during the movement. If there was only one upper body movement that you could do, that would give you the biggest “bang for your buck”, I would advocate the pull-up (or chin-up).

Pull-ups also provide a true test of one’s strength. How many people these days can complete ten, proper pull-ups in one set, regardless of their bodyweight? Not very many I’d bet, and this includes the “muscleheads” at the local gym as well. There is a very solid reason that this exercise is a mandatory requirement for the US Marines and other elite forces around the world – that being that the exercise builds true strength, and lasting endurance.

Remember that pull-ups should always be done in proper form to gain the utmost out of every repetition. Amongst other things, correct form involves pulling with your back muscles rather than arms, and keeping your legs as still as you can. You should never use momentum to complete a rep. Allow your MUSCLES to complete the movement, rather than your ego. Most people avoid pull-ups because they find them to be too tough, and are forever stuck on the lat pull-down machines while achieving little by the way of back development and true strength. Don’t be one of these people. Master the pull-up and it’s variations fully, and you will move to an elite level of strength that few people these days will ever attain in a lifetime of training.

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How to Choose the Health Nutrition Supplements Your Body Needs

Everyone understands that health nutrition supplements provide the user with proteins, vitamins, minerals, and many other nutrients that his body requires. Taking them in correct doses keeps a person energetic, and burns off the unwanted fat in the body. These are reasons enough to make the taking of these supplements a habit. Besides that, there is another logic to having health nutrition supplements.

Taking it routinely subjects you to some sort of discipline so that you are unlikely to deviate from the diet plan while you are having it. These supplements do not come cheap and once you are spending money on them, you will be conscious of the need to see through the whole process the right way so that the money is not wasted.

The health nutrition supplements that you need will depend upon what you want to achieve. If you are a bit obese and want to shed some weight and be shapely, you might need to use just a far burner and protein powder that will help you to lose weight.

But if you want not just to lose weight but build up some muscle mass as well, it is best to invest in some form of testosterone booster as well as protein powders. If you have some vitamin deficiencies, that should also be taken into consideration while choosing your health nutrition supplements.

Multivitamin supplements are a must, whatever your diet plan is, and whatever your goal is. It is a must for the smooth running of the various organs of the body, for burning extra fat by turning the body into an excellent fuel burning device, and for removing body toxins. The building blocks in multivitamin supplements help in repairing the wear and tear of the body as well. Most of the health nutrition supplements that you need will be available at local pharmacies or GNC stores.

Health nutrition supplements can be purchased online as well. These do not come cheap and you should first of all understand which are the ones that your body needs. Some people are under the erroneous impression that the more supplements one takes, the faster will the weight loss regimen progress. Nothing can be more far from the truth.

Nutrition supplements can only be taken in the correct amounts, after precisely identifying the need of the body. Whether you plan to buy health nutrition supplements online or offline, you will see heaps of them everywhere. It will be available as tablets, powders, bars, pills, and energy drinks. Choosing the right one from that jumble is your job.

You might have to go through a blood check or a thorough check done by your physician to find out exactly what your body needs to achieve what you want.

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3 Different Stages of Muscle Building You Need to Know

Before you jump head long into any muscle building training program you must know the three basic principles of what it takes to garner those big rippling biceps! After you have begun to understand the process of how the body goes through different stages of building muscle only then will you be able to initiate into a long-term muscle building training regiment.

Muscle Stimulation

The first phase is referred to as muscle stimulation. It is within this phase that you will learn how the audio treats its muscles when it comes to adding on lean muscle mass to compensate for previous failures. This may sound a bit contradictory but this is how the body works on a muscle to improve its maximum of elegy to either left or move something of massive weight. The body breaks down the muscle in order to compensate for the over strenuous activities of the weightlifting exercise only days before.

Learn about Nutrition

The second phase is to learn all you can about nutrition and what your body needs to grow big giant muscles. When you have a diet that’s full of fruits and vegetables and good wholesome grains and wheat and vitamins you’ll develop a body that is fit for ‘Schwarzenegger School of Bodybuilding Studs’ in California. If you do not treat your body like a temple that it is and you are trying to work out and negate the nutritional-aspect then the workout will be left unaffected and you will not gain muscles that all the girls at the beach want you to do. As long as you know that you need to eat a healthy, nutritious diet then your workout regimen will be just fine and your body will reward you with muscles upon muscles.

Learn the Golden Rule of Working Out then Resting

Many of the most-novices of muscle builders understand that you have to rest the body. Especially any of the targeted-muscles that you have just worked out the day before in order for them to grow into ‘anything’ bigger. Time and time again well-intentioned sincere young men who want to add muscle mass onto a relatively lean-body structure will forget this golden rule and work out every day religiously.

They do not give their muscles the time needed and required to produce more muscle tissue to make up for the failure of the past. The bottom line is that you should rest every day in between the weekly workout days and a good schedule beyond would look like this: Monday Wednesday Friday workout Tuesday Thursday rest, Saturday and Sunday cardiovascular workout or spend some time with the family. The most dependable factor you will need to learn of these three factors and three different stages of muscle growing experiences will be to be committed to your cause. Those guys and gals that one add-on muscle fiber to their body learn and follow these three phases of any workout regimen and are rewarded with fine tuned and muscular bodies.

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Gain Weight by Eating Healthy Food

Being underweight is as destructive as being overweight. Being too skinny may directly affect your work and personality. It can also lead to health issues in the long run. Several medical conditions such as thyroid problems can be responsible for a person being skinny. While some people can be naturally skinny and healthy, it is difficult for some to gain weight easily. It takes several days to gain weight; it is not an overnight job. Slowly and steadily weight can be increased while maintaining a proper health balance.

The most important thing to do in this scenario is to have a better caloric intake. These 5 tips may come handy for those aiming at gaining weight in a healthy way.

1. Intake of maximum proteins: Out of the top tips to gain weight, the most important is eating plenty of proteinous foods. As muscle mass is made out of protein, eating calories in terms of proteins is vital.

Without protein, those extra calories from the food might end up in excess of body fat. High protein foods like legumes and nuts can be helpful. Eating sufficient amounts of proteins can help in gaining muscle weight instead of body fat. A high protein diet thus helps in gaining muscle weight by acting as a building block.

2. Eat carbohydrates and fat: Eating a diet rich in carbohydrates and fat is essential to gain weight. Each meal should consist of proper portions of carbohydrates, fat, and proteins. Your meal intake should be at least 3 times each day. Make sure the food contains energy-dense snacks along with these 3 meals. This ensures plenty of carbohydrates, fat, and proteins. Eating healthy food acts as catalyst for gaining weight.

3. Energy-packed food: Eating energy-packed food is a healthy way to gain weight. These nutritious food items include nuts like Almonds, Walnuts, Peanuts, etc and dried fruits like raisins, etc.

Whole grain food like brown rice and oats are very useful to gain weight in a healthy way. Potatoes and sweet potatoes can be included in the diet, as well. Such a diet is highly filling and hence, split it in appropriate time intervals so that you don’t have to force the food inside you. Squeeze in some extra snacks or meals whenever possible.

4. Regular exercise: Gymming is just one of the ways for you to build muscles and gain weight. If a gym is not suitable, opt for any other kind of exercise regime like Yoga or Zumba. Also, try and play your favourite sport / game whenever possible. This will ensure that the food you eat is properly digested and converted into energy, further building your body strength and muscle.

5. Do not drink water before meals: Drinking water before meals reduces your intake quantity and in-turn hunger. For proper digestion, make sure to drink water 30 minutes after having meals.

Eating the right kind of fat is extremely important. Trans fats should be avoided and healthy fats should be consumed. Underweight individuals often wonder how to gain weight fast! Luckily, the answer is very simple: just eat right portions of the right food at right intervals of time.

Consume organic and fresh food for better results in putting on those extra calories. Make sure to buy organic food from the most authentic organic food supplier, only!

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Vitamin B Functions – Sources and Deficiencies

Vitamin B refers to a group of 8 vitamins. They are vitamin B1 (Thiamine), Vitamin B2 (Riboflavin), Vitamin B3 (Niacin), vitamin B5 (Pantothenic acid), vitamin B6 (Pyridoxine), vitamin B7 (Biotin), vitamin B8 (myo-inositol), vitamin B9 (Folic acid) and vitamin B12 (Cobalamin). Vitamin B plays a significant role in cell metabolism. At initial phase, scientists consider it is an individual vitamin much like we call vitamin A or vitamin C. However later in time, several scientific researches proved that they are cluster of chemically distinctive vitamins that may coexist in certain foods. Nutritional supplements containing all of the eight vitamins are referred to as vitamin B complex. On the other hand, nutritional supplement consisting of single vitamin B component is referred to specific name.

Vitamin B Functions

Vitamin B functions effectively for providing a whole host of health benefits. It maintains and boost up the metabolism rate. It also aids in maintaining healthy skin and offers flexibility in the muscle tone. Vitamin B functions well in managing a healthy immune system and it also offers a hale and hearty nervous system functioning. Vitamin B affects cell division and cell metabolism. It also affects the production of red blood cells. A deficiency in vitamin B may lead to anemia. Vitamin B complex is essential for fighting against different symptoms of stress, anxiety, depression and cardiovascular diseases.

All of the B vitamins are water soluble; however, a six year of vitamin B12 storage was seen in the liver, regardless of its water soluble nature.

Vitamin B Sources

The supply of vitamin B is abundant in nature. You can easily add it in your diet list. The natural sources may include potatoes, chili peppers, bananas, liver oil, tuna, lentils, tempeh, turkey and liver. Molasses and nutritional yeast are known sources of vitamin B.

Vitamin B Deficiencies

Inadequate supply of sufficient B-vitamins may lead to vitamin B deficiencies. It may cause different types of health complications. Lack of Thiamin or vitamin B1 may cause Beriberi. The typical symptoms may include weakness, disorder in nervous system, significant weight loss, irregular heart beat, and edema. Vitamin B deficiencies may also result in ariboflavinosis. Poor supply of vitamin B2 in diet may cause this complication. The common symptoms may include hypersensitivity to sunlight, edema, cheilosis, hyperemia and oral mucosa. Pellagra is another health complications occurred as a result of vitamin B deficiencies.

Niacin plays a major role here. Lack of niacin in regular diet may ensure the possibility of this health complication. Common symptoms may include aggression, dermatitis, confusion, insomnia and diarrhea. In severe cases, pellagra may cause mortality also.

Not so common in every day practice, but a deficiency in Pantothenic acid may cause vitamin B deficiencies. It may result in acne and paresthesia. A lack in pyridoxine supply may lead to a whole host of health complications. All of these complications are known health complications arising from vitamin B deficiencies. The common complications are depression, mood disorder, hypertension, anemia, water retention, and increased level of homocysteine. Inadequate supply of Biotin may result in vitamin B deficiencies that largely affect infants. It may lead to developmental disorder and neurological disorder among children. Folic acid deficiency may lead to an increased level of homocysteine, which may lead to birth defects during pregnancy. Deficiency in vitamin B12 may result in megaloblastic anemia, memory loss and cognitive decline.

Several studies are going on in the support of possible health benefits provided by vitamin B supplements. Studies reveal that folic acid may be found beneficial in preventing birth defects and combating against colorectal cancer. Additionally, it is documented that high levels of folate in combination with other vitamin supplements may actually reduce the risk of breast cancer. Typically clinical trials put emphasis on the combination of folate and vitamin B6 that are helpful in minimizing the potential risk factors triggering breast cancer. It is naturally available in green leafy vegetables such as spinach, broccoli and asparagus.

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What Are Body Building Supplements?

We easily get attracted towards people with smart personalities. Tough body, biceps, six packs abs, broad chest and other features of a good body is a dream of every person. It is often said that your body language speaks about your personality and so it is really essential to have a good body built. Why everyone of us do not have a rocking body built but Celebrities and athletes tend to have a flexible and strong body in their own way? Well! People having smart bodies work on their body postures day in and out. Body building Supplements are the building stones of a rigid and smart body.

Body building Supplements are useful for athletes and those who love to have a tough and healthy body. Basically Body building Supplements are those substances that help to tone the muscles and give a perfect shape to the body by increasing the strength of body. Building Supplements are also taken during weight lifting in order to loose fat. Follow the rule of eat less and work more, your intake and output should be balanced enough to maintain a good body balance. Eating healthy food, having a good sleep, exercising and proper intake of Body building Supplements will surely help a person to remain fit and lead a healthy life.

Building Supplements required for a healthy body can be consumed in any form like capsules, tablets, liquids or even powdered form. Some people who do not consume Supplements feel that intake of Supplements either change or interrupt the natural hormonal levels but this is not true.

Body Supplements generally include Vitamins, proteins,hormones and other ingredients required. Using Supplements in correct way and adequate amount surely reflect on your body texture. Nowadays several online informative sites are also giving valuable information about body Supplements, weight loss products, tips and several other related things.

So you need not necessarily visit a gym or fitness center but having bodybuilding supplements [http://www.no2max.com] in adequate amount will surely keep you fit and fine!

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Advantages and Disadvantages of Using Garcinia Cambogia for Weight Loss

Let’s start by discussing some of the benefits of garcinia cambogia. This all natural supplement serves the body in the following ways:

A Fat Blocker

Hydroxycitric acid (HCA), a citric acid byproduct, is the main active ingredient in Garcinia Cambogia extract. HCA blocks fat by inhibiting the efforts of citrate lyase, an important metabolic enzyme. This is one of the reasons that Garcinia is so successful as a weight loss supplement.

An Appetite Suppressant

A second important aspect of Hydroxycitric acid is its ability to suppress the appetite. It does this by increasing serotonin levels in the body. Serotonin is an important brain chemical that acts as a neurotransmitter. It is responsible for a number of regulatory processes that affect appetite and mood. You will not feel the urge to eat more than what is necessary to maintain a healthy weight.

A Metabolism Booster

One of the greatest benefits of Garcinia Cambogia is the ability to create a more efficient metabolism. The metabolic process is actually a sequence of chemical reactions that keep the body in a constant state of imbalance. HCA helps to balance these reactions and make the process more efficient.

As a result, the body uses more energy than it takes in. This causes it to tap the fat stores for fuel. This extraordinary supplement reduces fat and keeps excess weight down.

A Blood Cholesterol Reducing Agent

As HCA stops the citrate lyase enzyme from transforming sugars into fats, it blocks fat production and storage. At the same time, it reduces the amount of lipids in the blood stream. It lowers production of bad cholesterol and increases the production of good cholesterol.

So, when you take a Pure Garcinia Cambogia capsule, you are in fact waging a war against fat cells which are clinging stubbornly to your vital organs. These fat cells are harmful to your body and contribute to worse health.

A few things to be aware of:

  • Caution is advised in patients with diabetes (high blood sugar) or hypoglycemia (low blood sugar), and in those taking drugs, herbs, or supplements that can affect blood sugar.
  • Rhabdomyolysis (serious and potentially fatal disease involving degeneration of skeletal muscle) has been reported three hours after ingestion of a weight-loss herbal medicine containing a combination of ma huang (ephedrine), guarana (active alkaloid caffeine), chitosan, Gymnenasylvestre, Garciniacambogia (50% HCA), and chromium.
  • Garcinia is not recommended for use in pregnant or breastfeeding women due to a lack of available scientific evidence. Plus, you don’t want your baby’s appetite being suppressed!
  • As mentioned above, Garcinia Extract may lower blood sugar levels so caution is advised when using medications that can lower blood sugar. Patients taking drugs for diabetes should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.

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